Coevolution at the proteome scale - Institute for Protein Design
Coevolution at the proteome scale - Institute for Protein Design
Today we report in Science the identification of hundreds of previously uncharacterized protein–protein interactions in E. coli and the pathogenic bacterium M. tuberculosis. These include both previously unknown protein complexes and previously uncharacterized components of known complexes. This research was led by postdoctoral fellow Qian Cong and included former Baker lab graduate student Sergey Ovchinnikov, now a John Harvard Distinguished Science
Co-evolutionary landscape at the interface and non-interface regions of protein-protein interaction complexes - ScienceDirect
Gene expression of functionally-related genes coevolves across fungal species: detecting coevolution of gene expression using phylogenetic comparative methods, BMC Genomics
Structural prediction of protein interactions and docking using conservation and coevolution - Andreani - 2020 - WIREs Computational Molecular Science - Wiley Online Library
Protein interaction networks revealed by proteome coevolution
Recent advances in predicting and modeling protein–protein interactions: Trends in Biochemical Sciences
Computed structures of core eukaryotic protein complexes
Computed structures of core eukaryotic protein complexes
Proteomics, phylogenetics, and coexpression analyses indicate novel interactions in the plastid CLP chaperone-protease system - ScienceDirect
Protein interaction networks revealed by proteome coevolution
From sequence to function through structure: Deep learning for protein design - Computational and Structural Biotechnology Journal
Predicting Proteome-Scale Protein Structure with Artificial Intelligence